Drew's Biohack Bulletin

Hey Fitlifer!

If your energy’s been glitching and your holiday mood feels like it needs a software update, don’t worry — you’re not broken, you’re just low on the two things humans forget most: B12 and gratitude.

This week we’re digging into both, and trust me, the science is way cooler than the turkey.

Here's what we're diving into today (9-minute read):

• 💪 Your Body’s Quiet Cry For B12 — Are You Missing The Signs?

• 🦃 The Science Behind That Warm Fuzzy Holiday Feeling

• 🚨 This Weeks Breaking Health News

• It’s CYBER MONDAY! Stack codes DREW + CYBERMONDAY

If you’d like to enter to win the next giveaway, tell us what you want to hear about at the bottom of this newsletter.

💪Your Body’s Quiet Cry For B12. Are You Missing The Signs?

If you’ve been tired for no reason, zoning out mid-conversation, or getting random tingles in your hands and feet… your body might be flashing a big neon sign that says:

“HEY… WE’RE LOW ON B12.”

B12 keeps your energy, nerves, mood, and brain running smoothly — but absorption drops with age, gut issues, meds, and plant-based diets. Signs you might be low on B12:

• Unexplained exhaustion (low oxygen delivery)

• Tingling/numbness (nerve insulation weakens)

• Brain fog + forgetfulness

• Weak muscles or dizziness

• Pale/yellowish skin

• Smooth or sore tongue

• Mood dips (lower serotonin/dopamine)

• Vision changes

A simple blood test confirms it — and once corrected, most symptoms improve quickly. Until then here are some natural ways to boost B12 the smart, science-backed way

Eat High-B12 Foods

• Wild salmon

• Sardines

• Eggs

• Grass-fed beef

• Plain Greek yogurt

• Clams (the heavy hitter)

Quick B12 Breakfast:
2–3 eggs + spinach + smoked salmon. Fast. Powerful. Delicious.

Support Your Gut - So You Can Actually Absorb B12

Because even the best diet won’t matter if your gut can’t absorb nutrients. Simple, effective gut habits:

• Eat slowly

• Add fermented foods

• Reduce processed foods

• Manage stress + alcohol

• Keep meals simple and whole

• Organifi Colostrum → helps strengthen gut lining and absorption

• Organifi Pure → supports the gut–brain axis + cognitive clarity

Your body isn’t failing — it’s sending notifications. Give it the B12 and gut support it’s asking for, and watch your energy, mood, and focus switch back on faster than your morning WiFi.

🦃 The Science Behind That Warm Fuzzy Holiday Feeling

Holiday season is basically the Super Bowl of gratitude — family, food, chaos, and that one uncle who forgets he’s not hosting a podcast. But here’s the wild part: your brain LOVES gratitude just as much as your stomach loves mashed potatoes. And science backs it.

What Gratitude Actually Does to Your Brain

When you practice gratitude (yes, even silently in your head), your brain lights up in the areas responsible for reward, emotional regulation, and stress reduction — including the prefrontal cortex, ventral striatum, and amygdala. Studies show gratitude can:

• Boost dopamine + serotonin (your natural mood elevators)

• Lower cortisol, your stress hormone

• Improve sleep quality

• Strengthen the immune system

• Increase feelings of connection (even with people who double-dip in the salsa)

Gratitude shifts your nervous system out of “threat mode” and into “rest and restore.”
It activates regions tied to emotional processing and improves the way your brain handles challenges.

Three Tiny Gratitude Habits That Actually Work

1. The 10-Second Morning Reset

Before grabbing your phone, name one thing you're grateful for. It could be your dog, your breath, your coffee, or the fact that you woke up on planet Earth and not in a Jurassic Park reboot.

This small pause sends a cascade of calming signals through your nervous system.

2. The Brain Rewire Trick

At the end of the day, replay one good moment for 20 seconds.
Your brain strengthens whatever you repeat — this is neuroplasticity 101.

3. The Gratitude Text

Send a quick “appreciate you” message to someone. It spikes oxytocin, the bonding hormone, in both your brains. Yes… science says you can literally make someone’s day better with a 5-second text.

Thanksgiving's over, but here's a challenge: keep the gratitude practice going. Right before your next meal or any random moment take one slow breath and silently say, "Thank you for this moment."

Your brain will release dopamine and serotonin, literally rewiring neural pathways for joy, resilience, and peace long after the holiday chaos fades. Tiny habit, big shift, better you.

🍼 How Is Botulism Getting Into Baby Formula? Here’s How To Keep Kids Safe. The U.S. is in the grips of a botulism outbreak tied to a premium infant formula brand. Dozens of babies have been affected as of November 19.

🔬 New Neuron Signaling Mechanism Reveals Safer Pathway For Pain Treatment. Researchers found that nerve cells communicate outside the cell with the enzyme VLK, which can alter proteins in the space between neurons, affecting how those cells send signals.

🫀Everyday Microplastics Could Be Fueling Heart Disease. Microplastics may be silently fueling heart disease by damaging the very cells that keep arteries healthy.

B12 keeps your cells running, and gratitude keeps the rest of you from turning into a holiday gremlin. Both are easy to miss when life gets loud.

Take a breath, fuel up, and notice the tiny things that make this season worth slowing down for. I’ll see you next week.

We’re in this together 🚀 
Drew Canole

PS: Want to win some Organifi products? Rate the newsletter (below) and let us know what you’re struggling with or want to learn next.